Acetonitrile market global industry analysis, size and. Produced mainly as a byproduct of manufacturing acrylonitrile, acetonitrile is a colorless liquid with an etherlike odor. Product name, current issue date, click on download. Acetonitrile cas no 75058 material safety data sheet. Common name acetonitrile english name acetonitrile cas number 75058 molecular weight 41. Procedures standard ph values of primary buffer sol utions in acetonitrilewater mixtures with 10, 30, 40, 50 and 70%ww of acetonitrile, phps, were measured by the iupac procedure 9. Safety data sheet sds acetonitrile, 15% solution 01. First aid measures general advice consult a physician. Acetonitrile metabolizes into cyanide over 2 to 8 hours, so symptoms or signs of toxicity may be delayed after significant exposures. Acetonitrile in water 20%, s4b thermo fisher scientific. Identification of the substancemixture and of the companyundertaking.
India veritas house, 70 mint road, fort, mumbai 400 001. Material safety data sheet for acetonitrile, product number. This colourless liquid is the simplest organic nitrile hydrogen cyanide is a simpler nitrile, but the cyanide anion is not classed as organic. If w b w f10, report breakthrough and possible sample loss. Acetonitrile, also known as methyl cyanide, cyanomethane or ethanenitrile, is a clear. Acetonitrile is the chemical compound with the formula ch3cn. Acetonitrile is the chemical compound with formula c2h3n. Flammability envelopes for methanol, ethanol, acetonitrile and toluene. Acetonitrile breaks down slowly in the body to release the cyanide ion. Higher concentrations can produce central nervous system depressi on, narcosis, and unconsciousness. Three volunteers were exposed for 4 hours at 40, 80, or 160 ppm acetonitrile. Acetonitrile safety data sheet according to federal register vol. Other information revision b, june 2015 the information contained herein is provided in good faith and is believed to be correct as of the date hereof.
Acetonitrile msds material safety data sheet or sds. Acetonitrile, also known as methyl cyanide or cyanomethane is a colorless chemical compound in liquid form having chemical formula ch 3 cn. Acetonitrile ch 3 cn, cas 75058, also known as methyl cyanide or cyanomethane, is the simplest organic nitrile. Sheet msds, available from ineos, for information on the chemical. Exposure to very high concentrations of acetonitrile can result in cyanide poisoning. This reagent is intended for nterminal protein sequencing applications.
We ask that users who download significant portions of the database cite the. Chemtrec 8004249300 outside usa 7035273887 1216 6th ave n kent wa 98032 phone. Acetonitrile 75058 5000 u003 no acrylonitrile 1071 100 u009 no chemical weapons convention. Volitization from soil surfaces and leaching into ground water is expected to be significant. If inhaled if breathed in, move person into fresh air. Differences between using acetonitrile and methanol for. It is also a hazardous chemical substance and regulated as such throughout most of the world. Material safety data sheets msds are available by using hpc standards catalog numbers to search for products.
Fire hazard, acute health hazard, chronic health hazard 16. Acetonitrile rs for hplc gold ultragradient grade 2. Inhalation of vapors irritates the respiratory tract. Acetonitrile hplc, fisher chemical fisher scientific. In industry, it is likewise used as a solvent for the manufacture of such products as pharmaceuticals. Material safety data sheet domestic phone 800 2373526. Show this safety data sheet to the doctor in attendance. Acetonitrile is the chemical compound with the formula ch 3 cn. At 40 ppm, odor was detected, after which olfactory fatigue was noted. Acetonitrile is produced primarily as an acrylonitrile manufacture byproduct. Acetonitrile is a clear, colorless liquid with a sweet, ethereal odor. Trifluoroacetic acid in acetonitrile msds msdsdigital. Flammability envelopes for methanol, ethanol, acetonitrile.
Other companies are charging thousands of dollars to set up accounts and give you access to their msds online database. Calculate concentration, c, of acetonitrile in the air volume. Msds material safety data sheets msds are available by using hpc standards catalog numbers to search for products. Your new online msds binder is a place for you to store the material safety data sheets you need to deploy. Chemical product and company identification product name. Inhalation move casualty to fresh air and keep at rest. This value indicates that acetonitrile will not significantly bioconcentrate in aquatic organisms or adsorb to suspended solids and sediments in. In a wellconducted study in mice, the oral ld50 of acetonitrile was calculated to be 617 mgkg. When acetonitrile and methanol are respectively mixed with water in the same ratio, the acetonitrilebased solution generally has a higher elution strength. A liquid is typically considered a nonconductive, static accumulator if its conductivity is below 100 psm 100x10e12 siemens per meter and is considered a semi conductive, static accumulator if its conductivity is below. Acetonitrile, hplc grade is a colorless liquid used in chemical laboratories as a polar aprotic solvent in organic synthesis, as well as a carrier mobile phase solvent.
Material safety data sheet acetonitrile section 1 chemical product and company identification msds name. In particular, in some cases where the mixture ratio is low, the same retention times can be achieved using acetonitrile with less than half the ratio of methanol, as can be seen for. It is used as a polar aprotic solvent in organic synthesis and in the purification of butadiene. It is mainly used as a polar aprotic solvent in purification of.
This colourless liquid is the simplest organic nitrile. Firstaid measures eyes rinse with plenty of water for at least 15 minutes and seek medical attention immediately. Consider cyanide antidote as clinically indicated, such as sodium thiosulfate and sodium nitrate. Acetonitrile is expected to weakly adsorb to most soils based on the koc value. Acetonitrile is the most basic and simple organic nitrile. Find msds or sds, a coa, data sheets and more information. Journal of loss prevention in the process industries. Cas 75058 acetonitrile gradient grade for liquid chromatography lichrosolv reag. Cyanomethane, ethanenitrile, ethyl nitrile, methanecarbonitrile, methyl cyanide. May cause coughing, dizziness, dullness, and headache. Registration number 75 05 8 200 835 2 608 001 00 3 01 2119477 38 xxxx 4. Material safety data sheet acetonitrile msds section 1. Cdc niosh pocket guide to chemical hazards acetonitrile. Closed cup as in any fire, wear selfcontained breathing apparatus pressuredemand niosh approved or equivalent, and full protective gear to prevent contact with skin and eyes.
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